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1

Redox control of iron regulatory protein 2 stability

Anja Hausmann, Julie Lee, Kostas Pantopoulos

Journal:

Year:

2011

Language:

english

File:

PDF, 412 KB

english, 2011

2

Regulation of iron transport and the role of transferrin

Konstantinos Gkouvatsos, George Papanikolaou, Kostas Pantopoulos

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2012

Language:

english

File:

PDF, 946 KB

english, 2012

3

Nitric Oxide || Nitric Oxide, Oxygen Radicals, and Iron Metabolism

Pantopoulos, Kostas

Year:

2000

Language:

english

File:

PDF, 2.20 MB

english, 2000

4

The IRP/IRE system in vivo: insights from mouse models

Wilkinson, Nicole, Pantopoulos, Kostas

Journal:

Frontiers in Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.58 MB

english, 2014

5

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in β-thalassemia mouse model

Garcia-Santos, Daniel, Hamdi, Amel, Saxova, Zuzana, Fillebeen, Carine, Pantopoulos, Kostas, Horvathova, Monika, Ponka, Prem

Journal:

Year:

2017

Language:

english

File:

PDF, 3.25 MB

english, 2017

6

Iron Status and the Acute Post-Exercise Hepcidin Response in Athletes

Peeling, Peter, Sim, Marc, Badenhorst, Claire E., Dawson, Brian, Govus, Andrew D., Abbiss, Chris R., Swinkels, Dorine W., Trinder, Debbie, Pantopoulos, Kostas

Journal:

Year:

2014

Language:

english

File:

PDF, 245 KB

english, 2014

7

Associations among Erythroferrone and Biomarkers of Erythropoiesis and Iron Metabolism, and Treatment with Long-Term Erythropoiesis-Stimulating Agents in Patients on Hemodialysis

Honda, Hirokazu, Kobayashi, Yasuna, Onuma, Shoko, Shibagaki, Keigo, Yuza, Toshitaka, Hirao, Keiichi, Yamamoto, Toshinori, Tomosugi, Naohisa, Shibata, Takanori, Pantopoulos, Kostas

Journal:

Year:

2016

Language:

english

File:

PDF, 837 KB

english, 2016

8

Prediction of hemoglobin levels in individual hemodialysis patients by means of a mathematical model of erythropoiesis

Fuertinger, Doris H., Kappel, Franz, Zhang, Hanjie, Thijssen, Stephan, Kotanko, Peter, Pantopoulos, Kostas

Journal:

Year:

2018

Language:

english

File:

PDF, 2.07 MB

english, 2018

9

Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)

Lazaridou, Maria, Christodoulou, Evi, Nerantzaki, Maria, Kostoglou, Margaritis, Lambropoulou, Dimitra, Katsarou, Angeliki, Pantopoulos, Kostas, Bikiaris, Dimitrios

Journal:

Year:

2020

Language:

english

File:

PDF, 3.05 MB

english, 2020

10

Basics and principles of cellular and systemic iron homeostasis

Katsarou, Angeliki, Pantopoulos, Kostas

Journal:

Molecular Aspects of Medicine

Year:

2020

File:

PDF, 1.92 MB

2020

11

Conditional disruption of mouse HFE2 gene: Maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin

Konstantinos Gkouvatsos, John Wagner, George Papanikolaou, Giada Sebastiani, Kostas Pantopoulos

Journal:

Year:

2011

Language:

english

File:

PDF, 1.83 MB

english, 2011

12

Iron absorption and distribution in TNFΔARE/+ mice, a model of chronic inflammation

Klaus Schümann, Nadia Herbach, Christina Kerling, Markus Seifert, Carine Fillebeen, Isabella Prysch, Jens Reich, Günter Weiss, Kostas Pantopoulos

Journal:

Journal of Trace Elements in Medicine and Biology

Year:

2010

Language:

english

File:

PDF, 354 KB

english, 2010

13

Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity

Jian Wang, Guohua Chen, Julie Lee, Kostas Pantopoulos

Journal:

BMC Molecular Biology

Year:

2008

Language:

english

File:

PDF, 981 KB

english, 2008

14

HO-1-mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues

Hillel Zukor, Wei Song, Adrienne Liberman, Jeannie Mui, Hojatollah Vali, Carine Fillebeen, Kostas Pantopoulos, Ting-Di Wu, Jean-Luc Guerquin-Kern, Hyman M. Schipper

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 1.51 MB

english, 2009

15

Iron Metabolism and the IRE/IRP Regulatory System: An Update

KOSTAS PANTOPOULOS

Journal:

Annals of the New York Academy of Sciences

Year:

2004

File:

PDF, 10.86 MB

2004

16

Oxidative Stress and Iron Homeostasis: Mechanistic and Health Aspects

Galaris, Dimitrios, Pantopoulos, Kostas

Journal:

Critical Reviews in Clinical Laboratory Sciences

Year:

2008

Language:

english

File:

PDF, 1.30 MB

english, 2008

17

Nitric oxide and the post-transcriptional control of cellular iron traffic

Kostas Pantopoulos, Günter Weiss, Matthias W. Hentze

Journal:

Trends in Cell Biology

Year:

1994

Language:

english

File:

PDF, 729 KB

english, 1994

18

The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL

Jian Wang, Kostas Pantopoulos

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2005

Language:

english

File:

PDF, 323 KB

english, 2005

19

Oxidation-induced ferritin turnover in microglial cells: role of proteasome

Jana Mehlhase, Grit Sandig, Kostas Pantopoulos, Tilman Grune

Journal:

Free Radical Biology and Medicine

Year:

2005

Language:

english

File:

PDF, 461 KB

english, 2005

20

Regulation of iron metabolism in the sanguivore lamprey Lampetra fluviatilis : Molecular cloning of two ferritin subunits and two iron-regulatory proteins (IRP) reveals evolutionary conservation of the iron-regulatory element (IRE)/IRP regulatory system

Øivind Andersen, Kostas Pantopoulos, Hung-Teh Kao, Martina Muckenthaler, John H. Youson, Vincent Pieribone

Journal:

Year:

1998

Language:

english

File:

PDF, 295 KB

english, 1998

21

Ribonucleases of diverse specificities in rabbit brain nuclei

Kostas PANTOPOULOS, John G. GEORGATSOS

Journal:

Year:

1992

Language:

english

File:

PDF, 698 KB

english, 1992

22

Mechanisms of Mammalian Iron Homeostasis

Pantopoulos, Kostas, Porwal, Suheel Kumar, Tartakoff, Alan, Devireddy, L.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.99 MB

english, 2012

23

A role for lysosomes in the turnover of human iron regulatory protein 2

Camille Dycke, Peggy Charbonnier, Kostas Pantopoulos, Jean-Marc Moulis

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2008

Language:

english

File:

PDF, 571 KB

english, 2008

24

Iron regulatory and bactericidal properties of human recombinant hepcidin expressed in Pichia pastoris

Vasiliki Koliaraki, Martha Marinou, Martina Samiotaki, George Panayotou, Kostas Pantopoulos, Avgi Mamalaki

Journal:

Year:

2008

Language:

english

File:

PDF, 856 KB

english, 2008

25

Hepcidin generated by hepatoma cells inhibits iron export from co-cultured THP1 monocytes

Bill Andriopoulos, Kostas Pantopoulos

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 219 KB

english, 2006

26

Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells

Carine Fillebeen, Martina Muckenthaler, Bill Andriopoulos, Martin Bisaillon, Zineb Mounir, Matthias W. Hentze, Antonis E. Koromilas, Kostas Pantopoulos

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 851 KB

english, 2007

27

Iron inhibits replication of infectious hepatitis C virus in permissive Huh7.5.1 cells

Carine Fillebeen, Kostas Pantopoulos

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 839 KB

english, 2010

28

Erratum to: Iron inhibits replication of infectious hepatitis C virus in permissive Huh7.5.1 cells [J Hepatol. 2010 Dec;53(6):995–999]

Carine Fillebeen, Kostas Pantopoulos

Journal:

Journal of Hepatology

Year:

2011

File:

PDF, 239 KB

2011

29

Reply to: Is there any association between HCV multiplication and iron induced liver injury in chronic hepatitis C?

Carine Fillebeen, Kostas Pantopoulos

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 211 KB

english, 2011

30

Reply to: Hepatocyte iron accumulation: A new string to ribavirin’s antiviral bow?

Carine Fillebeen, Kostas Pantopoulos

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 119 KB

english, 2011

31

Small-Molecule Inhibitors of HIF-2a Translation Link Its 5′UTR Iron-Responsive Element to Oxygen Sensing

Michael Zimmer, Benjamin L. Ebert, Christopher Neil, Keith Brenner, Ioannis Papaioannou, Antonia Melas, Nicola Tolliday, Justin Lamb, Kostas Pantopoulos, Todd Golub, Othon Iliopoulos

Journal:

Year:

2008

Language:

english

File:

PDF, 2.42 MB

english, 2008

32

The prolyl 4-hydroxylase inhibitor ethyl-3,4-dihydroxybenzoate generates effective iron deficiency in cultured cells

Jian Wang, Joan L Buss, Guohua Chen, Prem Ponka, Kostas Pantopoulos

Journal:

Year:

2002

Language:

english

File:

PDF, 184 KB

english, 2002

33

Unregulated brain iron deposition in transgenic mice over-expressing HMOX1 in the astrocytic compartment

Wei Song, Hillel Zukor, Shih-Hsiung Lin, Adrienne Liberman, Ayda Tavitian, Jeannie Mui, Hojatollah Vali, Carine Fillebeen, Kostas Pantopoulos, Ting-Di Wu, Jean-Luc Guerquin-Kern, Hyman M. Schipper

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 823 KB

english, 2012

34

Differences in activation of mouse hepcidin by dietary iron and parenterally administered iron dextran: compartmentalization is critical for iron sensing

Daba, Alina, Gkouvatsos, Konstantinos, Sebastiani, Giada, Pantopoulos, Kostas

Journal:

Journal of Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 572 KB

english, 2013

35

166 Oxidative stress mediates hepatic iron uptake in vitro and in vivo

Stephan Hegedüsch, Julia Mangin, Daniel Rost, Andreas Welker, Kostas Pantopoulos, Wolfgang Stremmel, Sebastian Mueller

Journal:

Year:

2003

Language:

english

File:

PDF, 146 KB

english, 2003

36

Regulation of cellular iron metabolism

Wang, Jian, Pantopoulos, Kostas

Journal:

Biochemical Journal

Year:

2011

Language:

english

File:

PDF, 1.75 MB

english, 2011

37

Oxygen-dependent secretion of a bioactive hepcidin-GFP chimera

Chachami, Georgia, Lyberopoulou, Aggeliki, Kalousi, Alkmini, Paraskeva, Efrosyni, Pantopoulos, Kostas, Simos, George

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 777 KB

english, 2013

38

Translational Regulation of Mammalian and Drosophila Citric Acid Cycle Enzymes Via Iron-Responsive Elements

Nicola K. Gray, Kostas Pantopoulos, Thomas Dandekar, Brian A. C. Ackrell and Matthias W. Hentze

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.41 MB

english, 1996

39

Activation of Iron Regulatory Protein-1 by Oxidative Stress in vitro

Kostas Pantopoulos and Matthias W. Hentze

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.54 MB

english, 1998

40

Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice

Sebastiani, Giada, Pantopoulos, Kostas

Journal:

Year:

2011

Language:

english

File:

PDF, 2.83 MB

english, 2011

41

A high-fat diet modulates iron metabolism but does not promote liver fibrosis in hemochromatotic Hjv −/− mice

Padda, Ranjit Singh, Gkouvatsos, Konstantinos, Guido, Maria, Mui, Jeannie, Vali, Hojatollah, Pantopoulos, Kostas

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2015

Language:

english

File:

PDF, 10.26 MB

english, 2015

42

Insights on Regulation and Function of the Iron Regulatory Protein 1 (IRP1)*

Wang, Jian, Chen, Guohua, Filebeen, Carine, Pantopoulos, Kostas

Journal:

Year:

2008

Language:

english

File:

PDF, 645 KB

english, 2008

43

[Progress in Nucleic Acid Research and Molecular Biology] Progress in Nucleic Acid Research and Molecular Biology Volume 48 Volume 48 || The Role of the 5′ Untranslated Region of Eukaryotic Messenger RNAs in Translation and Its Investigation Using Antisense Technologies

Pantopoulos, Kostas

Year:

1994

Language:

english

File:

PDF, 3.21 MB

english, 1994

44

Iron regulation of hepcidin through Hfe and Hjv: Common or distinct pathways?

Pantopoulos, Kostas

Journal:

Year:

2015

Language:

english

File:

PDF, 552 KB

english, 2015

45

NTBI unveiled by chelatable fluorescent beads

Sebastiani, Giada, Pantopoulos, Kostas

Journal:

Biochemical Journal

Year:

2014

Language:

english

File:

PDF, 100 KB

english, 2014

46

Nitric Oxide Signaling to Iron-Regulatory Protein: Direct Control of Ferritin mRNA Translation and Transferrin Receptor mRNA Stability in Transfected Fibroblasts

Kostas Pantopoulos and Matthias W. Hentze

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.28 MB

english, 1995

47

Redox control of iron regulatory proteins

Fillebeen, Carine, Pantopoulos, Kostas

Journal:

Year:

2002

Language:

english

File:

PDF, 465 KB

english, 2002

48

The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta2-microglobulin

WANG, Jian, CHEN, Guohua, PANTOPOULOS, Kostas

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 280 KB

english, 2003

49

Inhibition of transferrin receptor 1 transcription by a cell density response element

Wang, Jian, Chen, Guohua, Pantopoulos, Kostas

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 495 KB

english, 2005

50

IRP1 Ser-711 is a phosphorylation site, critical for regulation of RNA-binding and aconitase activities

FILLEBEEN, Carine, CALTAGIRONE, Annie, MARTELLI, Alain, MOULIS, Jean-Marc, PANTOPOULOS, Kostas

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 577 KB

english, 2005